Explains the concept of the gut-brain axis, and its implications for health and disease. Describes how microbes and their metabolites communicate with the body and the brain. Explains how the microbiome-gut-brain axis influences the development of neurodegenerative, neuropsychiatric, and neurodevelopmental disorders. Describes how microbial metabolites regulate immune and metabolic pathways in the body, and how this may impact risk of allergies, autoimmune diseases, obesity and diabetes. Explains how the ecology of the oral microbiome impacts both gut and systemic health; discusses implications for modern-day oral healthcare. Lists potential microbial and gut health disruptors, as well as therapeutic strategies to improve gut and brain health (to become “ecosystem engineers”). Describes ways in which the highly complex gut-brain scientific research has been oversold and misinterpreted by the lay press. Identifies red flags of “pseudoscience” to become a healthy skeptic. Describes how the information in this course can be utilized to improve patient care and patient outcomes.

Describes the pharmacologic differences among cannabis (marijuana), THC and cannabinoids. Discusses the major legal issues surrounding THC at the Federal and State levels. Lists the physiologic and pathologic effects of marijuana (THC) including effects of long term use and potential harm to the adolescent brain. Describes FDA-approved uses for medical marijuana and possible clinical uses for cannabis in chronic pain patients. Explains the known dangers of vaping marijuana and development of EVALI (Lung Injury Due to E-Cigarettes and Vaping). Recognizes the signs and symptoms of acute marijuana intoxication. Discusses the myths and realities surrounding the explosion of CBD products across the country. Describes how the information in this course can be utilized to improve patient care and patient outcomes. Describes, for this course, the implications for dentistry, mental health, nursing, and other healthcare professions.

Describes components of the immune system and principles of normal immune function. Reviews the clinical features of common autoimmune, allergic and inflammatory conditions. Explains potential immune factors that may contribute to depression and other psychiatric disorders. Describes the link between poor oral health and immune dysfunction. Lists the dietary, pharmacologic, and lifestyle changes that may help balance immune function. Describes how the information in this course can be utilized to improve patient care and patient outcomes. Describes, for this course, the implications for dentistry, mental health, nursing, and other healthcare professions.