Describes the pharmacologic differences among cannabis (marijuana), THC and cannabinoids. Discusses the major legal issues surrounding THC at the Federal and State levels. Lists the physiologic and pathologic effects of marijuana (THC) including effects of long term use and potential harm to the adolescent brain. Describes FDA-approved uses for medical marijuana and possible clinical uses for cannabis in chronic pain patients. Explains the known dangers of vaping marijuana and development of EVALI (Lung Injury Due to E-Cigarettes and Vaping). Recognizes the signs and symptoms of acute marijuana intoxication. Discusses the myths and realities surrounding the explosion of CBD products across the country. Describes how the information in this course can be utilized to improve patient care and patient outcomes. Describes, for this course, the implications for dentistry, mental health, nursing, and other healthcare professions.